TABLE 1.
Combinations of linalool and meropenem (μg/ml) |
KPC-KP |
Type of interaction | |||
MICO | FIC | FICI | FICIc | ||
Linalool | 11,250 | 5,625 | 0.50 | 1.00 | Additive |
Meropenem | 32.00 | 16.00 | 0.50 |
MICO, MIC of one component alone; FIC, MIC of one component in the most effective combination; FICI, FIC index of one component in the most effective combination; FICIc, total FICI of the combination of both components. FICIc ≤ 0.5, synergistic; FICIc > 0.5–4.0, additive; FICIc > 4.0, antagonistic.