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. 2021 Mar 30;11:7162. doi: 10.1038/s41598-021-86562-y

Table 2.

IC50 values of dual-target compounds against M. tuberculosis LeuRS and MetRS.

IC50 (µM)
LeuRS MetRS
2 76.5 ± 66 115 ± 3
13 263.5 ± 0.7 122 ± 26
17* 13 13.8
27 ND 148.5 ± 33.2

The shown data represent mean values ± s.d. (n = 3).

*Data of IC50 for compound 17 from the previous article22.

ND not determined.