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. 2021 Mar 17;8:634177. doi: 10.3389/fmed.2021.634177

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Copyright © 2021 Gu, Huang, Avula, Caruso, Drysdale, Vessey, Ou, Fowler, Liu, Lin, Horton, Masters, Wiley, Guymer and Fletcher.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of glatiramer acetate treatment on monocytes phagocytosis isolated from those with and without RPD and its correlation with RPD area. (A) Graph showing phagocytic function before and after 10-min application of glatiramer acetate in monocytes isolated from healthy controls, subjects with intermediate AMD without RPD (RPD⁻) and subjects with intermediate AMD with RPD (RPD⁺). P-values from a Two-way ANOVA with post-hoc Tukey's analysis analysis are shown on top of each panel. (B) Correlations of RPD area with phagocytic function following glatiramer acetate treatment in subsets of monocytes. There was no significant correlation between RPD area and glatiramer acetate stimulated phagocytosis. ns: no significance.