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. 2021 Mar 17;15:636764. doi: 10.3389/fnins.2021.636764

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Copyright © 2021 Caba, Lehman and Caba-Flores.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Activation of Fos- (A,B) and Per1(C)-ir cells in the median preoptic nucleus (MnPO) and in the organum vasculosum of lamina terminalis (OVLT) in relation to nursing (yellow vertical line). Panel (A) shows the location of the MnPO and OVLT. (B) At the time of nursing Fos increases in both OVLT (red line) and MnPO (blue) with a further increase 1.5 h after in the MnPO. (C) Per1 increases in both OVLT and MnPO 4–8 after nursing, but this rhythm persists in un-nursed pups only in the MnPO (dashed blue line). Modified from Moreno et al., 2013, 2014. ac, anterior commissure; OC, optic chiasma.