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. 2021 Mar 17;15:650082. doi: 10.3389/fnins.2021.650082

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Copyright © 2021 Liu, Lepage, Kim, Jeon, Kim, Simon, Tanaka, Yuan, Islam, Peng, Arutyunyan, Surento, Kim, Jahanshad, Styner, Toga, Barkovich, Xu, Evans and Kim.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pial surface significantly enhanced (visually closer to true GM-CSF boundary) after a gradient-based refinement. Green curves represent the pial surface before refinement, and red curves represent the pial surface after refinement.