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. 2021 Mar 17;11:605884. doi: 10.3389/fonc.2021.605884

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Copyright © 2021 Ai, Wei, Wu, Tang, Li and Zou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LBX1-AS1 inhibits proliferation and invasion of OSCC cells by interacting with miR-182-5p and upregulating FOXO3 expression. (A, B) Cell proliferation in OSCC cell lines SCC-4 and CAL-27 was assessed using CCK-8 assay (A) and EdU assay (B). (C) Cell invasion of OSCC cell lines SCC-4 and CAL-27 was assessed by Transwell invasion assay. All experiments were performed three times. **P < 0.01 and ***, ^###P < 0.001 as indicated, ns, no significance. **/*** and ns vs. Control, ### vs. p-LBX1-AS1+miR-182-5p NC.