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. 2021 Mar 17;11:605884. doi: 10.3389/fonc.2021.605884

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Copyright © 2021 Ai, Wei, Wu, Tang, Li and Zou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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RBPJ-OE Mφ-Exos inhibit tumor growth by LBX1-AS1/miR-182-5p/FOXO3 pathway in mouse xenograft tumor model. (A) The level of LBX1-AS1 was detected by qRT-PCR. (B) The level of miR-182-5p was detected by qRT-PCR. (C) The level of FOXO3 was detected by qRT-PCR. (D) Representative images of xenograft tumors (three mice per group) in nude mice. (E) Tumor volume is monitored every 7 days for 35 days. (F) The weights of xenograft tumors are summarized. *P < 0.05, **P < 0.01 and ***P < 0.001 for statistical differences.