TABLE 1.

The regulation of microbial function in the high AFP chickens comparing to the low AFP chickens.

Pathway ID	KEGG pathway class	Pathway	Down expression genes	Up expression genes
ko01100	Global and overview maps	Metabolic pathways	–	307
ko01220	Global and overview maps	Degradation of aromatic compounds	–	5
ko00600	Lipid metabolism	Sphingolipid metabolism	–	10
ko00052	Carbohydrate metabolism	Galactose metabolism	–	23
ko00680	Energy metabolism	Methane metabolism	–	24
ko00190	Energy metabolism	Oxidative phosphorylation	–	20
ko00400	Amino acid metabolism	Phenylalanine, tyrosine and tryptophan biosynthesis	–	18
ko00195	Energy metabolism	Photosynthesis	1	–
ko00260	Amino acid metabolism	Glycine, serine and threonine metabolism	12	–
ko00460	Metabolism of other amino acids	Cyanoamino acid metabolism	6	–
ko00740	Metabolism of cofactors and vitamins	Riboflavin metabolism	4	–
ko00261	Biosynthesis of other secondary metabolites	Monobactam biosynthesis	5	–
ko00621	Xenobiotics biodegradation and metabolism	Dioxin degradation	1	–
ko00540	Glycan biosynthesis and metabolism	Lipopolysaccharide biosynthesis	6	8
ko00511	Glycan biosynthesis and metabolism	Other glycan degradation	8	19
ko00440	Metabolism of other amino acids	Phosphonate and phosphinate metabolism	3	4
ko00780	Metabolism of cofactors and vitamins	Biotin metabolism	6	10
ko00790	Metabolism of cofactors and vitamins	Folate biosynthesis	7	11
ko00130	Metabolism of cofactors and vitamins	Ubiquinone and other terpenoid-quinone biosynthesis	4	5