Table 2.

Multivariate logistic regression analysis for response to nCRT.

Variables	Hazard Ratio (95% CI)	P
Chemotherapy during the interval between nCRT and surgery
Yes	1.837 (1.047–3.224)	0.034
No
Pretreatment CEA (µg/L)
≥5	0.424 (0.236–0.761)	0.004
<5
Pretreatment biomarkers
PLR	0.992 (0.987–0.998)	0.013
PNI	1.181 (1.071–1.300)	0.001

nCRT, neoadjuvant chemoradiotherapy; CEA, carcinoembryonic antigen; PLR, platelet to lymphocyte ratio; PNI, prognostic nutritional index. Bold values mean that P value is significant.