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. 2021 Mar 31;12:220. doi: 10.1186/s13287-021-02288-8

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Angiogenesis assessment in the wound. a IHC staining of CD31 (40 × 10) showed more microvessels on the wound in the topical and IV groups compared with the control group at days 3, 7, 10, and 14. b The microvessel density in the wound at days 3, 7, 10, and 14. Values are mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001