FIGURE 2.

Overall snapshot of adaptive and innate immune cells in PVATs along the time-course of development and progression of hypertension. Immunophenotyping of mesenteric resistance PVAT (MRPVAT) and thoracic aortic PVAT (APVAT) in male and female Dahl S rats fed a control diet (CD) or a HFD for 10 (A,D), 17 (B,E), or 24 (C,F) weeks. Bars represent means ± SEM for the absolute cell counts of each immune cell type, normalized to tissue weight (in milligram). Number of animals is indicated by N. A P < 0.05 by two-way ANOVA with Tukey’s test for multiple comparison, was considered statistically significant. * and † inside the stacks in the graph represent a significant difference in the specific stack of immune cells between the sexes within each diet and between the diets within each sex respectively. * and † outside the stacks in the graph represent a significant difference in the sum total of immune cells between the sexes within each diet and between the diets within each sex respectively.