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. 2021 Mar 17;12:632767. doi: 10.3389/fphar.2021.632767

TABLE 2.

Toxicity of MG.

Activity Cell lines Dosage Application References
Inhibition of cell viability U937 and LO-2 cells 10–100 μM In vitro Chen H et al. (2019)
Inhibition of cell viability MMECs 50–200 μg ml−1 In vitro Wei et al. (2014)
Inhibition of cell migration VSMCs 40 μM In vitro Karki et al. (2013a)
Inhibition of cell viability Murine 3T3-F442A predipocytes and human normal subcutaneous predipocytes 30–100 μM In vitro Alonso-Castro et al. (2011)
Inhibition of cell growth mES-derived endothelial-like cells 50–100 μM In vitro Kim GD et al. (2013)
Inhibition of cell viability MCF-10A, MCF-7, SK-BR3, MDA-MB-453, MDA-MB-435S, MDA-MB-231, and MDA-MB-468 cells IC50: 70.52 ± 5.09, 36.46 ± 2.38, 59.40 ± 8.24, 35.69 ± 4.91, 25.39 ± 3.26, 25.32 ± 2.72, and 24.79 ± 3.06 μM, respectively In vitro Liu et al. (2013)
Inhibition of cell viability HCT-116 cells 1–50 μM In vitro Park et al. (2012)
Inhibition of cell viability OC2 cells 20–100 μM In vitro Hsieh et al. (2018)
Inhibition of cell viability A549 cells 6.25–200 μM In vitro Wu et al. (2014)
Inhibition of cell viability DU145 and PC3 cells 40 and 80 μM In vitro McKeown et al. (2014)
Induction of cell apoptosis GBC cells 10–30 μM In vitro Li et al. (2015)
Induction of cell apoptosis SGC-7901 cells 10–300 μM In vitro Rasul et al. (2012)
Inhibition of cell proliferation SKOV3 and TOV21G cells 6.25–100 μM In vitro Chuang et al. (2011)
Inhibition of cell proliferation QBC939, SK-ChA-1, MZ-ChA-1, and RBE cells 20–160 μM In vitro Zhang FH et al. (2017)