TABLE 5.
Gene set enrichment analysis (KEGG-base) in the female.
| KEGG set | NES | FDR | Higher expression in HRFI or LRFI |
| Basal cell carcinoma | –2.11055 | 0.003972 | LRFI |
| Hedgehog signaling pathway | –2.0326 | 0.003453 | LRFI |
| Neuroactive ligand receptor interaction | –1.84756 | 0.026776 | LRFI |
| Melanogenesis | –1.8143 | 0.026804 | LRFI |
| Gap junction | –1.79889 | 0.023586 | LRFI |
| DNA replication | 2.19206 | 0.001313 | HRFI |
| Primary immunodeficiency | 2.084619 | 0.002965 | HRFI |
| Mismatch repair | 2.020003 | 0.003884 | HRFI |
| Intestinal immune network for IgA production | 1.974355 | 0.004076 | HRFI |
| Cell cycle | 1.955905 | 0.004391 | HRFI |
| B cell receptor signaling pathway | 1.7872 | 0.029919 | HRFI |
| Autoimmune thyroid disease | 1.783557 | 0.027321 | HRFI |
| Pyrimidine metabolism | 1.727826 | 0.045972 | HRFI |
| Porphyrin and chlorophyll metabolism | 1.718103 | 0.04515 | HRFI |
| One carbon pool by folate | 1.698381 | 0.049032 | HRFI |
NES, enrichment score; FDR, false discovery rate of the p-value.