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. 2021 Mar 31;24(1):1–13. doi: 10.3831/KPI.2021.24.1.1

Figure 1.

Figure 1

The involvement signaling pathways in modulation of renoprotective effects of troxerutin. PCNA, proliferating cell nuclear antigen; CFTR, cystic fibroblast transmembrane conductance regulator; CLC2, Chloride channel 2; NLRP3, Nod-like receptor subset inflammasome; CXCR4, C-X-C chemokine ligand 12 receptor 4; TXNIP, thioredoxin interaction protein; OX-2, cyclooxygenase-2; iNOS, inducible nitric oxide synthase; NOX2, NADPH oxidase 2; Nrf2, nuclear factor erythroid 2-related factor-2; ROS, reactive oxygen species; PARP, poly ADP ribose polymerase; NF-kB, nuclear factor kappa-light-chain-enhancer of activated B cells.