Table 2.
Correlation Analysis of Mismatch Repair Protein Deletion Types and Clinicopathological Characteristics
| PMS2/MLH1(-) n=41 | MSH2/MSH6 (-) n=21 | Total n=62 | P value | |
|---|---|---|---|---|
| Age | ||||
| >55 | 27(65.9%) | 15(71.4%) | 42 | 0.657 |
| ≦55 | 14(34.1%) | 6(28.6%) | 20 | |
| Gender | ||||
| Male | 18(43.9%) | 10(47.6%) | 28 | 0.993 |
| Female | 23(56.1%) | 11(52.4%) | 34 | |
| Location | ||||
| Left | 8(19.5%) | 4(19.0%) | 12 | 0.639a |
| Right | 27(65.9%) | 12(57.1%) | 39 | |
| Rectum | 6(14.6%) | 5(23.8%) | 11 | |
| Diameter | ||||
| ≦5 cm | 19(46.3%) | 8(38.1%) | 27 | 0.535 |
| >5 cm | 22(53.7%) | 13(61.9%) | 35 | |
| Lymphovascular invasion | ||||
| Absent | 27(65.9%) | 16(76.2%) | 43 | 0.403 |
| Present | 14(34.1%) | 5(23.8%) | 19 | |
| Extranodal extension | ||||
| Absent | 37(90.2%) | 20(95.2%) | 57 | 0.849 |
| Present | 4(9.8%) | 1(4.8%) | 5 | |
| T stage | ||||
| T1-3 | 16(39.0%) | 7(33.3%) | 23 | 0.872 |
| T4 | 25(61.0%) | 14(66.7%) | 39 | |
| N stage | ||||
| N0 | 27(65.9%) | 17(81.0%) | 44 | 0.584a |
| N1 | 11(26.8%) | 3(14.3%) | 14 | |
| N2 | 3(7.3%) | 1(4.8%) | 4 | |
| TNM stage | ||||
| I | 5(12.2%) | 4(19.0%) | 9 | 0.420a |
| II | 22(53.7%) | 13(61.9%) | 35 | |
| III | 14(34.1%) | 4(19.0%) | 18 | |
| Tumor grade | ||||
| I | 4(9.8%) | 1(4.8%) | 5 | 0.925a |
| II | 20(48.8%) | 11(52.4%) | 31 | |
| III | 17(41.5%) | 9(42.9%) | 26 | |
| Tumor type | ||||
| NOS | 32(78.0%) | 15(71.4%) | 47 | 0.781a |
| Medullary | 2(4.9%) | 1(4.8%) | 3 | |
| Mucinous | 7(17.1%) | 5(23.8%) | 12 |
Note: aFisher’s exact test.