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. 2021 Mar 31;19:132. doi: 10.1186/s12967-021-02798-2

Table 3.

Association between type of treatment and clinical variables

Clinical variables ICIs CHTs n p-value*
SARS-CoV2 IgG/IgM
 IgG and/or IgM+ 9 39 885 0.04
 IgG and IgM− 278 559
Gender
 Male 154 207 885 < 0.001
 Female 133 391
Age (years)
 < 70 194 416 885 n.s
 ≥ 70 93 182
Cancer stage
 I–III 38 97 804 0.05
 IV 249 420
ECOG performance status
 0 244 265 793 < 0.001
 1–4 41 243
Lymphopenia
 Yes 2 90 755 < 0.001
 No 256 407
Leukopenia
 Yes 0 91 764 < 0.001
 No 258 415

ICIs Immune Checkpoint Inhibitors Treatment, CHTs chemotherapy treatments, n number of patients, n.s not statistically significant

*The p-values represent χ2 tests of independence indicating associations between type of treatment and categorical clinical variables (statistically significant p < 0.05)