Figure 2.

Scatter plot of percent of ipsilateral lung with combined perfusion/ventilation low-function receiving ≥20 Gy and average dose to lower ipsilateral lung for patients with grade 0 to 1 radiation-induced lung toxicity (RILT; white circles) versus grade 2 to 5 RILT (red diamonds). The estimated RILT risk based on logistic regression analysis is overlaid (shaded red) and the 20% risk threshold is explicitly shown (dotted red line). Independent functional (combined perfusion/ventilation low-function receiving ≥20 Gy) and locational (average dose to lower ipsilateral lung ≥20 Gy) radiation sensitivities are hypothesized based on these results. (A color version of this figure is available at https://doi.org/10.1016/j.adro.2021.100666.)