. 2021 Feb 7;6(3):100666. doi: 10.1016/j.adro.2021.100666

Table 3.

Receiver operating characteristic analysis for combined Q/V and dose multivariate model

Structure	Metric	Odds ratio	95% confidence interval	P-value	Area under the curve (95% confidence interval)
Lungs-GTV	ADL, Gy	1.15–	1.05–1.27	0.004	0.65 (0.52–0.78)
Lungs-GTV	Low Q/V ≥20 Gy, %	1.19–	1.06–1.36	0.006	0.65 (0.52–0.78)
Ipsilateral lung-GTV	ADL, Gy	1.06–	1.01–1.10	0.011	0.75 (0.63–0.87)
Ipsilateral lung-GTV	Low Q/V ≥20 Gy, %	1.10–	1.04–1.17	0.002	0.75 (0.63–0.87)
Contralateral lung-GTV	ADL, Gy	1.51–	1.06–2.17	0.022	0.31 (0.14–0.48)
Contralateral lung-GTV	Low Q/V ≥20 Gy, %	0.90–	0.44–1.37	0.687	0.31 (0.14–0.48)

Abbreviations: ADL = average dose to the lower region of lung structure in Gy; GTV = gross tumor volume; low Q/V ≥20 = Q/V low-function volume, defined as the intersection between low-function Q and low-function V, that received ≥20 Gy as a percent of the total lung structure volume; Q = perfusion; V = ventilation.