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. 2021 Mar 30;4(3):e213467. doi: 10.1001/jamanetworkopen.2021.3467

Table 2. Latent Profiles and 6-Month Outcomes of Well-being.

Outcome SWLS QOLIBRI-OS
Model 1, B (95% CI)a P value Model 2, B (95% CI)b P value Model 1, B (95% CI)a P value Model 2, B (95% CI)b P value
F 18.41 <.001 26.40 <.001 21.37 <.001 47.16 <.001
R2 0.12 0.22 0.14 0.32
Age (y) −0.02 (−0.04 to .01) .27 −0.031 (−0.056 to −0.001) .03 −0.009 (−0.012 to −0.005) <.001 −0.009 (−0.013 to −0.003) .001
Age (quadratic) 0.02 (<0.01 to 0.01) .03 0.001 (−0.001 to 0.002) .42 <0.001 (<0.001 to 0.001) <.001 <0.001 (<−0.001 to<−0.001) .01
Education (y) 0.36 (0.23 to 0.50) <.001 0.22 (0.09 to 0.36) .001 0.06 (0.04 to 0.07) <.001 0.022 (0.005 to 0.038) .03
Education (quadratic) 0.04 (0.02 to 0.06) .02 0.04 (0.02 to 0.06) .001 NA NA
Sex −0.09 (−0.91 to 0.73) .83 0.46 (−0.32 to 1.24) .25 −0.13 (−0.21 to −0.03) .01 −0.11 (−0.23 to 0.01) .06
Race (vs White)
Unknown 0.15 (−1.39 to 1.69) .85 0.11 (−1.35 to 1.56) .89 0.04 (−0.16 to 0.24) .68 0.23 (.01 to 0.44) .04
Black −3.47 (−4.52 to −2.41) <.001 −2.70 (−3.71 to −1.69) <.001 −0.37 (−0.51 to −0.23) <.001 −0.05 (−0.20 to 0.11) .57
Psychiatric history 4.43 (3.50 to 5.36) <.001 3.09 (2.19 to 3.99) <.001 0.65 (0.53 to 0.77) <.001 0.21 (0.07 to 0.34) .003
TBI severityc
GCS 13-15
CT− 1.62 (−0.12 to 3.35) .07 2.49 (0.83 to 4.16) .003 0.01 (−0.22 to 0.24) .91 0.59 (0.34 to 0.84) <.001
CT+ 1.78 (−0.04 to 3.60) .06 2.42 (0.69 to 4.16) .005 −0.05 (−0.28 to −0.20) .72 0.42 (0.16 to 0.69) .002
GCS 9-12 0.83 (−1.95 to 3.62) .56 1.13 (−1.50 to 3.76) .40 −0.04 (−0.41 to 0.33) .83 0.13 (−0.28 to 0.53) .54
Latent profile d
Emotionally resilient NA NA 7.46 (6.28 to 8.63) <.001 NA NA 1.07 (0.89 to 1.25) <.001
Cognitively impaired NA NA 5.12 (3.93 to 6.32) <.001 NA NA 0.40 (0.21 to 0.59) <.001
Cognitively resilient NA NA 3.62 (2.57 to 4.67) <.001 NA NA 0.63 (0.47 to 0.79) <.001

Abbreviations: CT, computed tomography; GCS, Glasgow Coma Scale; NA, not applicable; QOLIBRI-OS, Quality of Life after Brain Injury-Overall Scale; SWLS, Satisfaction With Life Scale; TBI, traumatic brain injury.

a

Model 1 independent variables were age, sex, race, education, psychiatric history (reference group is those with a psychiatric history), and TBI severity.

b

Model 2 entered the same independent variables as model 1 with the addition of neurobehavioral latent class membership.

c

Reference Group is severe TBI (GCS 3-8).

d

Reference group is neuropsychiatrically distressed class.