Table 6.
Association of total plasma EETs and DHETs with fasting plasma insulin measured on average 5.4 years later in the Strong Heart Family Study.
| GMR* | 95% CI | p^ | |
|---|---|---|---|
| 14,15-EET | 0.99 | (0.95, 1.04) | 0.76 |
| 11,12-EET | 1.00 | (0.95, 1.05) | 0.95 |
| 8,9-EET | 0.99 | (0.95, 1.04) | 0.73 |
| 5,6-EET | 0.99 | (0.95, 1.04) | 0.70 |
| 14,15-DHET | 0.98 | (0.94, 1.03) | 0.42 |
| 11,12-DHET | 0.99 | (0.94, 1.03) | 0.55 |
| 8,9-DHET | 0.99 | (0.94, 1.05) | 0.84 |
| 5,6-DHET | 1.00 | (0.94, 1.06) | 0.90 |
Abbreviations: EET=Epoxyeicosatrienoic Acid; DHET= Dihydroxyeicosatrieonic acid
The analyses included adjustments for age, sex, site, education, smoking, physical activity, BMI (Kg/m2), waist circumference and LDL levels.
⁎
GMR: Geometric mean ratios of plasma insulin associated with one SD higher log EET/DHET species.
^
Inverse probability-of-being-sampled weighted Generalized Estimating Equations (GEE) regression Wald test with robust sandwich variance-covariance under a family cluster-specific exchangeable working correlation structure, and results from multiple imputations combined using Rubin's rules