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. 2021 Feb 19;296:100437. doi: 10.1016/j.jbc.2021.100437

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© 2021 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Retina defects in zebrafish. A, hematoxylin and eosin (HE) staining of retinas in the yars2^+/+, yars2^+/−, and yars2^−/− zebrafish at 5 dpf. GCL, ganglion cell layer; INL, inner nuclear layer; IPL, inner plexiform layer; ONL, outer nuclear layer; OPL, outer plexiform layer; RPE, retinal pigment epithelium. The angle brackets colored in red denoted the ONL. Scale bar, 50 μm. Shorter outer segments in the cones and rods were indicated. B, cones and rods in the retinal cross sections of yars2^+/+, yars2^+/−, and yars2^−/− zebrafish at 5 dpf, stained with lectin PNA-488 (green, yellow arrows) and 1D4/Rhodopsin (red, white arrows) and DAPI (blue) staining for nuclei. Scale bar, 10 μm.