Table 2:
Populations and COVID-19 outcomes for alpha-1 blocker (T) and 5ARI/PDE5 (C) user cohorts. We report population size, total exposure time, outcome events (Covid diagnosis, hospitalization, and intensive services) and minimally detectable risk ratio (MDRR). MDRR is provided only for Covid diagnosis due to the space constraint. The database abbreviations are defined under the heading Data Sources in the Method section.
| Patients | Time (years) | Diagnosis | Hospital | Intensive | MDRR (Diagnosis) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| T | C | T | C | T | C | T | C | T | C | ||
| Stratified analysis | |||||||||||
| SIDIAP | 11,793 | 1,318 | 4,162 | 471 | 334 | 51 | 132 | 20 | 0 | 0 | 1.61 |
| VA | 360,802 | 54,723 | 189,564 | 29,642 | 1,854 | 236 | 636 | 96 | 111 | 12 | 1.20 |
| CUIMC | 2,414 | 582 | 338 | 84 | 27 | <5 | 16 | <5 | 0 | 0 | 4.53 |
| OpenClaims | 1,995,594 | 366,734 | 817,994 | 160,225 | 4,809 | 767 | 2.621 | 407 | 0 | 0 | 1.11 |
| Optum DOD | 241,842 | 39,032 | 56,438 | 9.613 | 193 | 47 | 131 | 35 | 18 | 6 | 1.69 |
| Optum EHR | 15,275 | 2,136 | 1,031 | 149 | 50 | 7 | 32 | 5 | <5 | 0 | 3.10 |
| Matched analysis | |||||||||||
| SIDIAP | 8,994 | 1,315 | 3,211 | 471 | 275 | 51 | 115 | 20 | 0 | 0 | 1.59 |
| VA | 312,522 | 54,642 | 165,688 | 29,600 | 1,485 | 236 | 495 | 96 | 92 | 12 | 1.21 |
| CUIMC | 1,873 | 520 | 261 | 74 | 18 | <5 | 11 | <5 | 0 | 0 | 6.58 |
| OpenClaims | 1,873,014 | 365,534 | 774,635 | 159,742 | 4,351 | 764 | 2,361 | 407 | 0 | 0 | 1.11 |
| Optum DOD | 218,032 | 38,988 | 51,451 | 9,602 | 175 | 47 | 118 | 35 | 18 | 6 | 1.69 |
| Optum EHR | 12,303 | 2,114 | 848 | 148 | 33 | 7 | 19 | 5 | <5 | 0 | 3.50 |