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. 2021 Mar 1;16(3):415–426. doi: 10.2215/CJN.07270520

Table 5.

Factors associated with change in peritubular capillary density among patients with delayed graft function (n=61)

Clinical Characteristics Mean Change, % (SD) Unadjusted Difference in Change, % (95% Confidence Interval) P Value Difference in Change Adjusted for Pretransplant Peritubular Capillary Density, % (95% Confidence Interval) P Value Fully Adjusted Difference in Change, % (95% Confidence Interval)a P Value
Peritubular capillary density on the preimplantation biopsy per 1% higher −0.9 (−1.0 to −0.8) <0.001 −0.9 (−1.0 to −0.8) <0.001 −0.8 (−0.9 to −0.7) <0.001
Donor type
 Neurologically deceased −3.8 (4.4) 0 0 0
 Living −6.4 (2.7) −2.5 (−6.7 to 1.8) 0.25 0.6 (−2.6 to 1.4) 0.55 1.0 (−1.1 to 3.1) 0.32
 Cardiocirculatory arrest −3.4 (3.3) 0.2 (−2.3 to 2.7) 0.85 0.9 (−0.3 to 2.1) 0.12 2.0 (0.5 to 3.5) 0.01
Donor BP
 Normal BP −3.6 (4.3) 0 0 0
 Donor hypertension −4.9 (3.6) −1.7 (−4.1 to 0.8) 0.18 −1.2 (−2.3 to −0.0) 0.05 −1.1 (−2.1 to −0.1) 0.04
Recipient statin use
 No statin use at transplant −4.3 (3.7) 0 0 0
 Statin at time of transplant −3.3 (4.7) 0.9 (−1.2 to 3.1) 0.38 0.9 (−0.1 to 1.8) 0.09 1.1 (0.3 to 2.0) 0.02
Biopsy type
 For cause −7.6 (4.5) 0
 Surveillance −3.4 (3.9) 3.6 (0.2 to 7.0) 0.04 2.3 (1.0 to 3.6) <0.001 1.4 (−0.1 to 2.9) 0.06
Modality of graft transportation
 Cold storage −4.6 (3.7) 0 0 0
 Hypothermic perfusion −2.6 (4.6) 1.9 (−0.2 to 4.0) 0.08 1.3 (0.4 to 2.3) 0.005 0.9 (−0.1 to 1.8) 0.06
Cold ischemia time per 1 h higher 0.2 (0.0 to 0.4) 0.02 0.2 (0.1 to 0.4) 0.02 0.2 (0.0 to 0.3) 0.02
a

In addition to the variables included in the table, estimates are adjusted for biopsy size to correct for technical variations in measurement.