Table 5.
Clinical Characteristics | Mean Change, % (SD) | Unadjusted Difference in Change, % (95% Confidence Interval) | P Value | Difference in Change Adjusted for Pretransplant Peritubular Capillary Density, % (95% Confidence Interval) | P Value | Fully Adjusted Difference in Change, % (95% Confidence Interval)a | P Value |
---|---|---|---|---|---|---|---|
Peritubular capillary density on the preimplantation biopsy per 1% higher | −0.9 (−1.0 to −0.8) | <0.001 | −0.9 (−1.0 to −0.8) | <0.001 | −0.8 (−0.9 to −0.7) | <0.001 | |
Donor type | |||||||
Neurologically deceased | −3.8 (4.4) | 0 | 0 | 0 | |||
Living | −6.4 (2.7) | −2.5 (−6.7 to 1.8) | 0.25 | 0.6 (−2.6 to 1.4) | 0.55 | 1.0 (−1.1 to 3.1) | 0.32 |
Cardiocirculatory arrest | −3.4 (3.3) | 0.2 (−2.3 to 2.7) | 0.85 | 0.9 (−0.3 to 2.1) | 0.12 | 2.0 (0.5 to 3.5) | 0.01 |
Donor BP | |||||||
Normal BP | −3.6 (4.3) | 0 | 0 | 0 | |||
Donor hypertension | −4.9 (3.6) | −1.7 (−4.1 to 0.8) | 0.18 | −1.2 (−2.3 to −0.0) | 0.05 | −1.1 (−2.1 to −0.1) | 0.04 |
Recipient statin use | |||||||
No statin use at transplant | −4.3 (3.7) | 0 | 0 | 0 | |||
Statin at time of transplant | −3.3 (4.7) | 0.9 (−1.2 to 3.1) | 0.38 | 0.9 (−0.1 to 1.8) | 0.09 | 1.1 (0.3 to 2.0) | 0.02 |
Biopsy type | |||||||
For cause | −7.6 (4.5) | 0 | |||||
Surveillance | −3.4 (3.9) | 3.6 (0.2 to 7.0) | 0.04 | 2.3 (1.0 to 3.6) | <0.001 | 1.4 (−0.1 to 2.9) | 0.06 |
Modality of graft transportation | |||||||
Cold storage | −4.6 (3.7) | 0 | 0 | 0 | |||
Hypothermic perfusion | −2.6 (4.6) | 1.9 (−0.2 to 4.0) | 0.08 | 1.3 (0.4 to 2.3) | 0.005 | 0.9 (−0.1 to 1.8) | 0.06 |
Cold ischemia time per 1 h higher | 0.2 (0.0 to 0.4) | 0.02 | 0.2 (0.1 to 0.4) | 0.02 | 0.2 (0.0 to 0.3) | 0.02 |
In addition to the variables included in the table, estimates are adjusted for biopsy size to correct for technical variations in measurement.