Table 3.
Outcomes of kidney transplantations in Finland from June 2004 to December 2017 and the United States from January 2008 to August 2008 by quartiles of time from brain death to organ perfusion (procurement delay)
| Variable | Finland: Quartiles of Time from Brain Death to Organ Perfusion in Organ Donors | United States: Quartiles of Time from Brain Death to Organ Perfusion in Organ Donors | ||||||
|---|---|---|---|---|---|---|---|---|
| Quartile, n of transplantations | First, n: 596 | Second, n: 598 | Third, n: 597 | Fourth, n: 597 | First, n: 14,635 | Second, n: 14,828 | Third, n: 14,838 | Fourth, n: 14,641 |
| Delayed graft function | 233 (39%) | 222 (37%) | 204 (34%) | 190 (32%) | 6059 (24%) | 5614 (22%) | 5458 (22%) | 5944 (24%) |
| Acute rejection | 115 (19%) | 107 (18%) | 106 (18%) | 102 (17%) | NA | NA | NA | NA |
| 1-yr graft survival | 93% | 96% | 94% | 95% | 92% | 93% | 94% | 94% |
| 5-yr graft survival | 75% | 85% | 84% | 84% | 74% | 76% | 77% | 78% |
| 10-yr graft survival | 54% | 63% | 62% | 69% | 47% | 50% | 53% | 51% |
| Follow-up, median (IQR), yr | 4.1 (2.0–8.0) | 5.2 (2.7–9.0) | 5.3 (2.3–8.8) | 4.1 (1.7–7.0) | 4.2 (2.0–6.9) | 3.8 (1.7–6.0) | 2.9 (1.0–5.0) | 1.9 (0.7–3.8) |
| Graft survival, median, yr | 10.9 | 13.0 | >13.5a | 13.5 | 9.7 | 10.0 | 10.3 | 10.1 |
Graft survival is defined as alive with a functioning graft. NA, not available for the US cohort; IQR, interquartile range.
a
Over 50% of grafts were still functioning at the end of follow-up. Median (>13, 5 years) was thus not reached in follow-up. In graft survival, outcome is defined as death, retransplantation, or return to dialysis.