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. Author manuscript; available in PMC: 2021 Mar 31.
Published in final edited form as: Lancet Oncol. 2020 Mar;21(3):e135–e145. doi: 10.1016/S1470-2045(19)30795-8

Figure 3: Plasticity of macrophages.

Figure 3:

Illustration of the factors that convert a macrophage between a tumouricidal (M1) and immunosuppressive (M2) state, and the consequences of these changes. MHC=major histocompatibility complex. IL=interleukin.