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. 2021 Mar 31;21:142. doi: 10.1186/s12883-021-02164-1

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Skin biopsy samples underwent immunohistochemical staining: a hematoxylin-eosin staining (× 200 magnification), the arrows refer to eosinophilic spherical inclusion bodies in the nuclei of epithelial cells in small sweat gland cells; b anti-p62 immunohistochemical staining (arrows, × 200 magnification) and c anti-ubiquitin immunohistochemical staining (arrows, × 200 magnification). d Electropherograms showing GC-rich regions using PCR and repeat-primed PCR assays. e GC-rich PCR (GC-PCR) indicated the patient had 102 GGC repeats in the 5’ UTR of NOTCH2NLC