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Protein levels of cytokines measured by ELISA in the lungs of male and female mice after repeated subchronic exposure to NiNPs in the absence or presence of LPS. A) CXCL1 protein in BALF. B) IL-6 protein in BALF. C) CCL2 protein in BALF and lung lysates. (n=5–6 mice per group, ***P<0.001 or **P< 0.01 or *P<0.05 compared to vehicle determined by one-way ANOVA, ##P<0.01 or ###P<0.001 between sexes determined by two-way ANOVA).
