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. 2021 Mar 31;139:104814. doi: 10.1016/j.jcv.2021.104814

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© 2021 Elsevier B.V. All rights reserved.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 1 — Three-dimensional structure of the SARS-CoV-2 spike protein showing amino acid substitutions and deletions for major SARS-CoV-2 variants including the Marseille-4 variant.

Structure prediction was performed using the Phyre2 web portal (http://www.sbg.bio.ic.ac.uk/∼phyre2/html/page.cgi?id=index) and visualized using the Pymol tool v.1.8 (https://pymol.org/2/). Amino acid substitutions and deletions are showed with a country flag for the variants first detected in UK (20I/501Y.V1), South Africa (20 H/501Y.V2) and Brazil (20 J/501Y.V3), or with the label “Marseille-4.