Table 2.
Top 15 drugs predicted by the ET model that are known to be associated with peripheral neuropathy from SIDER
| InChIKey | Name | Known | Prediction probability |
|---|---|---|---|
| JURKNVYFZMSNLP-UHFFFAOYSA-N | Cyclobenzaprine (BRD-K42348709) | TRUE | 0.8592 |
| KRMDCWKBEZIMAB-UHFFFAOYSA-N | Amitriptyline (BRD-K53737926) | TRUE | 0.8311 |
| MJIHNNLFOKEZEW-UHFFFAOYSA-N | Lansoprazole (BRD-A49172652) | TRUE | 0.7613 |
| ZZVUWRFHKOJYTH-UHFFFAOYSA-N | Diphenhydramine (BRD-K47278471) | TRUE | 0.7153 |
| ZKMNUMMKYBVTFN-HNNXBMFYSA-N | Ropivacaine (BRD-K50938786) | TRUE | 0.582 |
| BCGWQEUPMDMJNV-UHFFFAOYSA-N | Imipramine (BRD-K38436528) | TRUE | 0.5591 |
| WUBBRNOQWQTFEX-UHFFFAOYSA-N | Aminosalicylic acid (BRD-K80267133) | TRUE | 0.4977 |
| YREYEVIYCVEVJK-UHFFFAOYSA-N | Rabeprazole (BRD-A39390670) | TRUE | 0.457 |
| PHTUQLWOUWZIMZ-GZTJUZNOSA-N | Dosulepin (BRD-K54759182) | TRUE | 0.3622 |
| XRECTZIEBJDKEO-UHFFFAOYSA-N | Flucytosine (BRD-K82143716) | TRUE | 0.3463 |
| ODQWQRRAPPTVAG-BOPFTXTBSA-N | Doxepin (BRD-K37694030) | TRUE | 0.3403 |
| UGJMXCAKCUNAIE-UHFFFAOYSA-N | Gabapentin (BRD-K62737565) | TRUE | 0.333 |
| KBOPZPXVLCULAV-UHFFFAOYSA-N | Mesalazine (BRD-K28849549) | TRUE | 0.3244 |
| GBXSMTUPTTWBMN-XIRDDKMYSA-N | Enalapril (BRD-K57545991) | TRUE | 0.3153 |
| HCYAFALTSJYZDH-UHFFFAOYSA-N | Desipramine (BRD-K60762818) | TRUE | 0.3102 |