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. Author manuscript; available in PMC: 2021 Mar 31.
Published in final edited form as: Thromb Haemost. 2018 Nov 12;118(12):2086–2097. doi: 10.1055/s-0038-1675228

Figure 3. The effect of rPLTP on platelet fibrinogen and aggregation.

Figure 3.

(A) SDS PAGE of His-tagged human rPLTP stained with Coomassie brilliant blue. (B) PLTP activity of rPLTP. (C) Flow cytometry analysis of fibrinogen binding on human platelet after rPLTP and ADP treatment. (D) and (E) the effect of rPLTP on ADP-induced mouse platelet aggregation. PLTP-deficient mouse PRP was treated with rPLTP (20 μg/mL) or BSA (20 μg/mL, control) and the aggregation was examined. (F) Dose effect of rPLTP on ADP-induced human platelet aggregation. (G) Dose effect of rPLTP on collagen-induced human platelet aggregation. Values represent the mean ± SD, n = 3–5, *P < 0.05, **P < 0.01.