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. Author manuscript; available in PMC: 2021 Mar 31.
Published in final edited form as: Thromb Haemost. 2018 Nov 12;118(12):2086–2097. doi: 10.1055/s-0038-1675228

Figure 4. Effect of PLTP on PS externalization.

Figure 4.

PS externalization was assessed by annexin V–FITC labeling followed by flow cytometry. (A) and (B) flow cytometry analysis and quantification of the effect of PLTP overexpression (Tg) on PS externalization on platelets. (C) Effect of PLTP deficiency on PS externalization. (D) The effect of rPLTP on PLTP deficient platelet PS externalization. (E) Effect of PLTP overexpression on shear-induced (SIPA) induced platelet aggregation. Flow cytometric plots for the measurement of platelet aggregation. SIPA was estimated as increase in platelet population outside the single platelet gate compared to static control mouse platelet rich plasma. (F) Flow cytometric plots for the measurement of platelet aggregation after gated with PE-CD61 for platelet population. Values represent the mean ± SD, n = 5–8, *P < 0.05, **P < 0.01.