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. 2021 Mar 17;11:642229. doi: 10.3389/fonc.2021.642229

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Copyright © 2021 Wei, Shi, Lin, Ma, Pang, Mao, Li, Lu, Wang and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Bioinformatic analysis showed ACLY is upregulated in A2780/CDDP cells. (A) ACLY was upregulated in A2780/CDDP cells compared with A2780 cells in GSE15709 dataset. (B) The volcano plot on DEGs between A2780 and A2780/CDDP in GSE15709 dataset. (C) The GO enrichment and KEGG enrichment of DEGs between A2780/CDDP and A2780, the filtering condition was p < 0.05. (D) KEGG enrichment of DEGs of GSE15709 calculated and weighted by rich factor. (E) Pathway viewer of PI3k/AKT, the red units mean upregulated in A2780/CDDP, and the green units mean downregulated in A2780/CDDP, the darker the color is, the less the P-value is. ***P < 0.001 for statistical analysis of the indicated groups.