Table 2.
Number of triggers observed per patient and their association with adverse drug reactions
| Number of triggers detected | Number of patients (n=400), n (%) | Patients without adverse events (n=327), n (%) | Patients with adverse events (n=63), n (%) | Yield of total (%) | P |
|---|---|---|---|---|---|
| 0 | 73 (18.25) | 73 (18.25) | 0 (0) | 0 | - |
| 1 | 36 (9) | 29 (7.25) | 7 (1.75) | 19.4 | 0.1697 |
| 2 | 79 (19.75) | 75 (18.75) | 4 (1) | 5.06 | 0.0001* |
| 3 | 51 (12.75) | 45 (11.25) | 6 (1.5) | 11.75 | 0.0184 |
| 4 | 65 (16.25) | 48 (12) | 17 (4.25) | 26.15 | 0.1262 |
| 5 | 38 (9.5) | 30 (7.5) | 8 (2) | 21.05 | 0.1005 |
| 6 | 23 (5.75) | 15 (3.75) | 8 (2) | 34.78 | 0.6827 |
| 7 | 13 (3.25) | 9 (2.25) | 4 (1) | 30.76 | 1.00 |
| 8 | 14 (3.5) | 8 (2) | 6 (1.5) | 42.85 | 1.37 |
| 9 | 8 (2) | 5 (1.25) | 3 (0.75) | 37.5 | 0.6212 |
Statistical significance was determined by Chi-square test. P<0.05 was considered statistically significant. *P<0.05 as compared between patients without adverse events and patients with adverse events