Table 2.
Genes were down-regulated 5 folds or more after androgen (MENT).
| Ontology | Symbol | Arbitrary count | |||
|---|---|---|---|---|---|
| CON | MENT | LH | LH+MENT | ||
| Cytokine | Cxcl12 | 3151 | 427(-7) | 477(-7) | 390(-8) |
| Ier5l | 552 | 50(-11) | 150(-4) | 253(-2) | |
| Xcl1 | 962 | 111(-9) | 554(-2) | 174(-6) | |
| Cxcl11 | 3126 | 506(-6) | 1715(-2) | 368(-9) | |
| Cxcl13 | 283 | 28(-10) | 961(+3) | 189(-0.5) | |
| Extracellular matrix | Slpi | 363 | 14(-26) | 872(+2) | 223(-2) |
| Mmp12 | 392 | 67(-6) | 880(+2) | 91(-4) | |
| Metabolism | Ubd | 6705 | 778(-9) | 3930(-2) | 776(-9) |
| Es1 | 11891 | 2051(-6) | 10641(-1.1) | 3524(-3) | |
| Protein binding | Sc65 | 562 | 91(-6) | 176(-3) | 221(-3) |
| Receptor binding | Cd74 | 439 | 18(-24) | 310(-1.3) | 10(-46) |
| Tmem178 | 910 | 133(-7) | 1149(+1.2) | 513(-2) | |
| Chi3l1 | 213 | 16(-13) | 110(-2) | 17(-13) | |
| Asgr1 | 315 | 48(-7) | 818 (+2) | 473(+1.4) | |
| Tmem15 | 153 | 27(-6) | 45(-3) | 65(-2) | |
| Ccr5 | 324 | 71 (-5) | 222(-1.3) | 116(-3) | |
| Signaling | Igtp | 788 | 164(-5) | 384(-2) | 246(-3) |
| Sh2d2a | 208 | 31(-7) | 56(-4) | 33(-6) | |
| Serpina3n | 2744 | 579(-5) | 2346(-1.2) | 1399(-2) | |
| Transcription factor | Snrpa | 1021 | 229(-5) | 1533(+1.5) | 558(-2) |
| Aif1 | 161 | 33(-5) | 92(-2) | 48(-3) | |
| Transporter | Pla2g2a | 7253 | 167(-43) | 4179(-2) | 781(-9) |
| Hpx | 12486 | 412(-30) | 11281(-1.1) | 3621(-3) | |
| S100a4 | 1588 | 415(-5) | 1027(-1.5) | 462(-3) | |
| Lcn2 | 4902 | 568(-8) | 3090(-1.5) | 1436(-3) | |
() Fold changes after MENT, LH or LH+MENT when compared to control (CON). 25 genes examined, of them, 12 genes were also down-regulated 2 folds or higher by LH treatment.