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. Author manuscript; available in PMC: 2021 Mar 31.
Published in final edited form as: Stat Med. 2020 Jul 27;39(26):3685–3699. doi: 10.1002/sim.8687

FIGURE 2.

FIGURE 2

Simulated latent biomarker trajectories for 10 random subjects. Panel (a): W1i (t). Panel (b): W2i (t). Panel (c): Latent continuous process α3i+KL3it+KD3iη3i(eη3it1) used to define the binary biomarker W3i (t).