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. Author manuscript; available in PMC: 2021 Mar 31.
Published in final edited form as: J Am Chem Soc. 2018 Sep 21;140(39):12424–12433. doi: 10.1021/jacs.8b05147

Figure 1.

Figure 1.

Generation of cR10-containing cell-permeable DUB ABPs. (a) Chemical steps of generating cell-permeable HA-Cys(cR10)-Ub-PA (2) probe. (b) ESI–MS characterization of probe 2. (c) Structure of cell-permeable probe HA-Cys(cR10)-Ub-VME (3) and HA-Cys(cR10)-Ub-EA (4).