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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Epilepsia. 2020 Aug 27;61(9):2010–2021. doi: 10.1111/epi.16617

Figure 3. Identification of strains resistant to epileptogenesis.

Figure 3.

(A) MST and (B) GST during 8-day flurothyl kindling. The order of the CC strains are ranked based on the value of kindling slope of myoclonic (A) and generalized (B) seizures, respectively. (C) Kindling slopes of MST and GST (R2=0.325, p<0.001) are correlated across strains except CC032. (D) Maximum behavioral seizure score during 30 min after each injection of PTZ (35 mg/kg, i.p.) every other day over 10-trial PTZ kindling (n=5). Data are presented as mean ± SEM and analyzed using two-way ANOVA with post hoc Tukey’s multiple comparisons test, **p<0.01.