Table 3.
Overview of regions showing altered functional connectivity in patients
Region | Overlap with cytoarchitectonic area | x | y | z | Z score | Cluster size |
---|---|---|---|---|---|---|
Decreased connectivity with left MTG | ||||||
R STG/STS/MTG | 66 | −24 | −2 | 5.64 | 1,307 | |
Decreased connectivity with left AG | ||||||
L IPC | PFma (14 % overlap) PGaa (13 % overlap) PGpa (11 % overlap) |
−50 | −59 | 57 | 4.81 | 659 |
L ITG | −71 | −41 | −18 | 5.02 | 422 | |
Decreased connectivity with Broca’region | ||||||
L VLPFC | Area 45b (13 % overlap) | −56 | 42 | −5 | 6.27 | 1,913 |
R VLPFC | 44 | 39 | −15 | 4.84 | 452 | |
L DLPFC | Area 44b (6 % overlap) | −35 | 20 | 51 | 5.65 | 1,612 |
L IPC | PFma (24 % overlap) PFa (13 % overlap) hIP1c (9 % overlap) hIP2c (21 % overlap) |
−45 | −45 | 45 | 4.33 | 658 |
Increased connectivity with Broca’sregion | ||||||
SMA | Area 6d (83 % overlap) | 0 | −5 | 59 | 5.27 | 667 |
L insula/putamen | −32 | −5 | 2 | 4.14 | 918 | |
Decreased connectivity with left thalamus | ||||||
R cerebellum | 5 | −78 | −27 | 4.96 | 632 | |
Increased connectivity with left thalamus | ||||||
L hippocampus/fusiform gyrus | SUBe (16 % overlap) hOC4vf (8 % overlap) |
−12 | −35 | −11 | 5.61 | 1,656 |
All activations p < 0.05 (cluster-level FWE corrected)
x, y, z coordinates refer to the peak voxel in MNI space, R right, L left