Table 1.
Participant characteristics overall and by participation in leisure-time physical activity in mid-life (Visit 1, 1987–1989), n = 326
| Participant characteristics | Participation in physical activity |
||
|---|---|---|---|
| Total (n = 326) | No (n = 126) | Yes (n = 200) | |
| Age, y, mean (SD) | 52.3 (5.2) | 52.1 (4.9) | 52.4 (5.4) |
| Female sex*, n (%) | 187 (57.4) | 84 (66.7) | 103 (51.5) |
| Black race*, n (%) | 135 (41.4) | 68 (54.0) | 67 (33.5) |
| APOE ε4 | |||
| 0 allele, n (%) | 224 (68.7) | 84 (66.7) | 140 (70.0) |
| 1 allele, n (%) | 94 (28.8) | 39 (31.0) | 55 (27.5) |
| 2 allele, n (%) | 8 (2.5) | 3 (2.4) | 5 (2.5) |
| <High school education*, n (%) | 52 (16.0) | 26 (20.6) | 26 (13.0) |
| Current smoker, n (%) | 57 (17.5) | 24 (19.0) | 33 (16.5) |
| Hypertension*, n (%) | 95 (29.3) | 41 (32.8) | 54 (27.1) |
| Diabetes*, n (%) | 18 (5.5) | 8 (6.4) | 10 (5.0) |
| Body Mass Index*, kg/m2, mean (SD) | 29.0 (5.4) | 30.1 (5.9) | 28.3 (4.9) |
| Late-life Cognitive Status | |||
| Normal, n (%) | 239 (73.3) | 92 (73.0) | 147 (73.5) |
| Mild cognitive impairment, n (%) | 87 (26.7) | 34 (27.0) | 53 (26.5) |
| Mid-life Meeting PA guidelines*, n (%) | 101 (31.0) | 0 (0.0) | 101 (50.5) |
| Mid-life MET. min. wk−1*, mean (SD) | 572.4 (750.9) | 0 (0.0) | 933.0 (763.4) |
| Late-life Participation in PA*, n (%) | 224 (68.7) | 69 (54.8) | 155 (77.5) |
| Late-life Meeting PA guidelines*, n (%) | 146 (44.8) | 38 (30.2) | 108 (54.0) |
| Late-life MET. min. wk−1*, mean (SD) | 667.0 (738.4) | 454.2 (623.8) | 801.1 (774.1) |
| Late-life Global SUVR, mean (SD) | 1.30 (0.26) | 1.32 (0.26) | 1.28 (0.26) |
| Late-life Elevated amyloid burden (SUVR>1.2)*, n (%) | 169 (51.8) | 75 (59.5) | 94 (47.0) |
*
p<0.05 for differences between participation in physical activity (yes/no). Characteristics are measured at mid-life (visit 1, 1987–1989) unless specified. SD, standard deviation; SUVR, standardized uptake value ratio; PA, physical activity. Mid-life, Visit 1 (1987–1989); Late-Life, Visit 5 (2011–2013).