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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Nat Rev Nephrol. 2020 Sep 16;16(11):686–696. doi: 10.1038/s41581-020-00335-w

FIG. 1: Overview of KPMP centers and the flow of KPMP data from different provenances.

FIG. 1:

Clinical data and pathology reports from recruitment centers, and molecular data and imaging data from tissue interrogation sites are integrated with data from the scientific literature and omics databases at the KPMP central hub using KPMP ontologies. Six recruitment sites enroll participants with common forms of acute and chronic kidney disease, and collect biosamples including a research kidney biopsy. Five tissue interrogation sites process and perform molecular analysis of participant biosamples. The central hub manages and aggregates data from all sites for systematic analysis, develops visualization tools and Application Programming Interfaces (APIs) to facilitate community access to data. Data harmonization and standardization with KPMP ontologies facilitate flexible data retrieval and analysis.