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. 2020 Jun 20;37(2):261–275. doi: 10.1007/s10565-020-09542-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a The expression of SOD1 and HIF-1α after MSM and DOX treatment. The expression was evaluated with RTqPCR. The results are expressed as a relative expression. b The expression of SOD1 on protein level. The expression was evaluated with Western blot and presented as representative results. p < 0.05 was considered statistically significant. *p < 0.05, **p < 0.01, ***p < 0.001 as compared to Cnt. ##p < 0.01, ###p < 0.001 as compared to MSM-treated cells. MSM methylsulfonylmethane, DOX doxorubicin, Cnt control