Table 2.
The relative expression of cleaved PARP1 (89 kDa) obtained in Western blot analysis
| Treatment | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Relative expression of cleaved PARP1 | 0.5 μM DOX | 1 μM DOX | 300 mM MSM | 400 mM MSM | 0.5 μM DOX + 300 mM MSM | 1 μM DOX + 300 mM MSM | 0.5 μM DOX + 400 mM MSM | 1 μM DOX + 400 mM MSM | Cnt |
| ISHIKAWA | |||||||||
| 0.998 | 1.549 | 0.738 | 1.385 | 1.028 | 1.336 | 0.879 | 0.841 | 1.000 | |
| MFE-296 | |||||||||
| 3.503 | 5.650 | 1.073 | 0.928 | 2.694 | 3.149 | 1.823 | 2.671 | 1.000 | |
| MFE-280 | |||||||||
| 1.624 | 2.632 | 2.077 | 2.203 | 3.571 | 3.123 | 5.268 | 6.624 | 1.000 | |
The results are expressed as mean of fold change of the expression normalized to control sample. The experiment was conducted in duplicate
MSM methylsulfonylmethane, DOX doxorubicin, Cnt control, PARP1 poly (ADP-ribose) polymerase-1