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. 2021 Feb 2;52(2):233–243. doi: 10.1007/s10735-020-09940-2

Fig. 1.

Fig. 1

Immunohistochemistry of all factors in WHO grade II tumors. Magnification: first column 1:10, scale bar 1000 µm, second column 1:40, scale bar 200 µm. a/b VEGF-A on tumor cells (asterisk) and tumor vessels (arrowhead). c/d vessel-dominant VEGF-A expression (arrowheads). E/F) VEGFR-1 on tumor vessels (arrowheads). g/h VEGFR-2 on tumor vessels (arrowheads indicating a vessel in G and an endothelial cell in H). j/k VEGFR-3 on tumor vessels (arrowheads). L/M) NRP-1 on tumor vessels (arrowheads). N/O) NRP-2 negative tumor vessels (arrowheads). Abbreviations: vascular endothelial growth factor (VEGF), VEGF-receptor (VEGFR), neuropilin (NRP)