. 2021 Apr 1;95(4):1179–1226. doi: 10.1007/s00204-021-03003-5

Table 7.

Natural and synthetic organoselenium compounds tested in animal models of AD

	Aβ-fragment 25–35	Sporadic AD^a	Triple- transgenic AD^b
Selenomethionine			++
Ebselen		++	++
p-Methoxyl- diphenyl diselenide	++	++

Aβ-fragment 25–35

Sporadic
AD^a

Triple- transgenic AD^b

Selenomethionine

Ebselen

p-Methoxyl-

diphenyl diselenide

^aIcv streptozotocin-induced Sporadic AD, ^bAPPswe, PS1M146V, and tauP301L

++ means effective