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. 2021 Mar 18;8:633590. doi: 10.3389/fmolb.2021.633590

TABLE 2.

The patterns of early TACE refractoriness in patients with HCC.

Characteristics Total (n = 204) Training cohort (n = 147) Validation cohort (n = 57) p Value
Viable lesions >50%, n (%) 47 (23.0%) 28 (19.0%) 19 (33.3%) 0.093
Presence of new lesions, n (%) 7 (3.4%) 4 (2.7%) 3 (5.3%) 0.390
Vascular invasion, n (%) 9 (4.4%) 4 (2.7%) 5 (8.8%) 0.074
Extrahepatic spread, n (%) 5 (2.5%) 5 (3.4%) 0 (0.0) -
Elevation of AFP, n (%) 31 (15.2%) 24 (16.3%) 7 (12.3%) 0.532

Note: TACE, transarterial chemoembolization; HCC, hepatocellularcarcinoma; AFP, alpha-fetoprotein.