Figure 1.

The removal of the omentum aggravates the systemic inflammation and reduces survival after CLP. (A) Mice were subjected to CLP or omentectomy+CLP (n = 20 per group). The survival rates were evaluated for consecutive 7 days after CLP. Statistical difference was determined by the log-rank test. At the 8 and 24 h after CLP, PLF and blood samples were collected, and the level of IL-6 (B), TNF-α (C), and IL-10 (D) (n = 9~10 per group) were determined. All values are shown as means ± SEM from 3 separate experiments. **p < 0.01 and *p < 0.05 for omentectomized vs WT.