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. 2021 Mar 18;9:640667. doi: 10.3389/fcell.2021.640667

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Copyright © 2021 Li, Chen, Kemper and Brigstock.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Proteomic analysis of EVs from AML12 cells. (A) Summary of quantitative features of EV proteins analyzed from AML12 cell EV samples. (B) The 30 most abundant proteins identified in AML12 cell EVs. (C) The 30 most enriched components identified by cellular component analysis of all EV proteins. (D) The top 30 pathways (from a total of 61 pathways) identified by KEGG pathway analysis of all EV proteins. (E) String analysis for entire proteome in AML12 cell EVs, important clusters were labeled.