Fig. 3. Gene interaction network analysis and microfluidic validation of SEBYL results.

A Functional clustering of 285 long-lived deletion mutants. Circles represent long-lived deletions; edges are published physical protein–protein interactions. Overrepresented categories are highlighted in designated colors. B RLS of designated strains of both a and alpha mating types combined. Average RLS is noted in parenthesis. p-value calculated by two-sided Mann–Whitney U test. ns not significant, **p < 0.01, ***p < 0.001. See Supplementary Data 3 for all statistical analysis on RLS experiments. See also Fig. S2.