Table 2.

Trend analysis in crude rates of the incidence and mortality of legionellosis per 100,000 population by sex, 1999–2017.

	Period 1		Period 2		Period 3		Entire study period
	Years	APC (95% CI)	Years	APC (%)	Years	APC (%)	Average APC (95% CI)
Incidence
All	1999–2007	32.3 (19.0 to 47.0)	2007–2017	11.1 (7.8 to 14.5)			20.1 (14.7 to 25.7)
Men	1999–2007	31.1 (19.1 to 44.4)	2007–2017	11.4 (8.3 to 14.6)			19.8 (14.9 to 24.9)
Women	1999–2004	−7.3 (−38.8 to 40.5)	2004–2007	101.5 (−44.1 to 626.7)	2007–2017	8.3 (3.7 to 13.1)	15.0 (−7.4 to 43)
Mortality
All	1999–2017	−5.9 (−8.1 to −3.5)					−5.9 (−8.1 to −3.5)
Men	1999–2007	−13.1 (−21.6 to −3.6)	2007–2011	11.5 (−17.8 to 51.3)	2011–2017	−14.5 (−21.9 to −6.5)	−8.6 (−15.5 to −1.3)
Women	1999–2017	−5.2 (−8.0 to −2.2)					−5.2 (−8.0 to −2.2)

APC annual percentage change, CI confidence interval.