Table 1.
Baseline demographic, clinical and laboratory characteristics of the two COVID-19 study groups.
| Hydroxychloroquine and oseltamivir N = 50 |
Favipiravir N = 50 |
p value | |
|---|---|---|---|
| Age (years): mean (SD) | 36.4 (11.5) | 36.3 (12.5) | 0.984 |
| Male sex: N (%) | 25 (50.0) | 25 (50.0) | 1.000 |
| Health care worker: N (%) | 31 (62.0) | 35 (70.0) | 0.527 |
| Contact with confirmed case: N (%) | 36 (72.0) | 37 (74.0) | 1.000 |
| Direct care of confirmed infected patients: N (%) | 29 (58.0) | 34 (68.0) | 0.407 |
| Comorbidities: N (%) | 9 (18.0) | 6 (12.0) | 0.575 |
| Relevant CT chest findings: N (%) | 12 (24.0) | 10 (20.0) | 0.809 |
| Hospital stays in days: mean (SD) | 12.4 (5.5) | 11.5 (5.3) | 0.408 |
| Haemoglobin (g/dL): mean (SD) | 13.4 (1.6) | 13.7 (1.7) | 0.424 |
| Total leukocyte count(× 109/L): mean (SD) | 5.5 (1.8) | 5.7 (2.2) | 0.512 |
| Neutrophils count (× 109/L): Mean (SD) | 6.6 (13.9) | 5.8 (11.4) | 0.741 |
| Lymphocytes count (× 109/L): mean (SD) | 3.9 (7.6) | 3.1 (6.8) | 0.627 |
| Platelets count (× 109/L): mean (SD) | 265.4 (95.4) | 229.2 (64.1) | 0.029 |
| Serum ferritin (µg/L): mean (SD) | 280.7 (296.0) | 201.5 (197.3) | 0.118 |
| Serum ferritin > 200/300: N (%) | 15 (30.0) | 14 (28.0) | 1.00 |
| D-dimer (ng/mL): Mean (SD) | 390.0 (359.3) | 785.7 (1103.1) | 0.018 |
| D-dimer > 250: N (%) | 28 (56.0) | 39 (78.0) | 0.033 |
| Lactate dehydrogenase (IU/L): mean (SD) | 205.7 (48.9) | 195.7 (54.9) | 0.337 |
| CK total (U/L): mean (SD) | 111.1 (74.1) | 94.2 (55.0) | 0.469 |
| Creatine kinase-MB (U/L): mean (SD) | 12.4 (6.3) | 14.2 (5.4) | 0.405 |